Global NeuroDiscovery Challenge

MIND THE DATA

Search for Gender Based Differences In Alzheimer’s Disease

 

Marietta Anthony, PhD

Marietta Anthony, PhD

Dr. Anthony’s expertise is in women’s health and drug development. She is a board member for Arizona
CERT, a non-profit research and education organization. Previously, she was director of Women’s Health
Programs for the Critical Path Institute and held senior positions in women’s health research and clinical
research at Georgetown University Medical Center. Earlier, she was director of research programs in the
National Institutes of Health Office of Research on Women’s Health; deputy director of the FDA Office of
Women’s Health; and managed expert panels on developing evidence-based clinical practice guidelines
at the Agency for Healthcare Research and Quality.

Marietta Anthony obtained a PhD in Medical Microbiology and Immunology from the UCLA School of Medicine where she conducted research on viruses that cause cancer. She completed a postdoctoral fellowship in the Department of Biological Chemistry at UCLA.

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Janine Austin Clayton, MD

Janine Austin Clayton, MD

Janine Austin Clayton, M.D., is the Director of the Office of Research on Women’s Health, National Institutes of Health (NIH), and Associate Director for Research on Women’s Health, NIH, in the NIH Office of the Director.

She is the author of over 80 scientific publications, journal articles, and book chapters. Prior to joining the Office of Research on Women’s Health, she was the Deputy Clinical Director of the National Eye Institute (NEI), NIH. A board certified ophthalmologist, Dr. Clayton’s research interests include autoimmune ocular diseases and the role of sex and gender in health and disease. Dr. Clayton has a particular interest in ocular surface disease and discovered a novel form of disease associated with premature ovarian insufficiency which affects young women.

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Howard-Fillit

Howard Martin Fillit, MD

A geriatrician and neuroscientist, Dr. Fillit is founding executive director and chief science officer
of the Institute for the Study of Aging, an Estée Lauder family foundation, and Alzheimer’s Drug
Discovery Foundation, a public charity. Both work to accelerate drug discovery for Alzheimer’s and
related dementias through venture philanthropy. He is a clinical professor of geriatrics, medicine
and neuroscience at The Rockefeller University and The Mount Sinai School of Medicine. His geriatric
medicine practice focuses on Alzheimer’s. He is author of more than 300 scientific/clinical publications
and senior editor of the leading international Textbook of Geriatric Medicine and Gerontology.

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Florence-Haseltine

Dr. Florence Haseltine, MD, PhD

Dr. Haseltine is a consultant to IT and biomedical companies. Her company, Haseltine Systems,
manufactures containers to protect wheelchairs. She also develops mobile apps for reproductive
sciences, including “Embryo,” honored by the National Library of Medicine. Earlier, she was director
of the Center for Population Research of the NIH National Institute of Child Health and Human
Development. She was founding editor of the Journal for Women’s Health and founder of the Society for
of Women’s Health Research. At Yale University she held positions in the Department of Obstetrics and
Gynecology. She is the current president of the Assembly of Scientists.

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Freda Lewis-Hall, MD

Dr. Lewis-Hall is executive vice president and chief medical officer of Pfizer Inc. Trained as a
psychiatrist, she has held leadership roles in academia, medical research, front-line patient
care, and at global biopharmaceutical companies. Prior to her work in industry, she led research
projects for the National Institutes of Health and was vice chairperson of the Department of
Psychiatry at Howard University College of Medicine. She serves on numerous boards. In 2010,
she was appointed by the Obama Administration to the inaugural Board of Governors for the
Patient-Centered Outcomes Research Institute, and in 2012 she was appointed chair of the Cures
Acceleration Network Review Board.

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Lenore Launer

Dr. Lenore Launer (NIH/NIA)

Dr. Launer is a Senior Investigator in the Intramural Research Program, the National Institute on Aging. She is Chief of the Neuroepidemiology Section in the Laboratory of Epidemiology and Population Studies. The Neuroepidemiology Section research focuses on understanding the contribution of genetic, inflammatory, metabolic, vascular, and hormonal factors to sub-clinical and clinical outcomes in brain disease and investigating the links between brain disease and other common diseases of old age. Dr.Launer is PI and Co-PI on several large cohort studies designed to take a life course approach to investigating the development of late age brain disease. Her research is conducted in the context of these large studies where hypotheses on risk/protective factors and mechanisms for brain disease tested, with the aim of identifying public health approaches to preventing late age cognitive impairment. She has authored over 350 articles and book chapters and is a member of the Steering Committees and Work Groups of several large NIH Prevention Trials.

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Michelle M. Mielke, Ph.D

Dr. Mielke received a Bachelor’s of Science in Neuroscience at the University of Pittsburgh and a doctorate in Psychiatric/NeuroEpidemiology from the Johns Hopkins University Bloomberg School of Public Health. She then completed a two-year fellowship as the Lydia Gillespie Clinical and Research Post-doctoral Fellow in Psychiatry at the Johns Hopkins University School of Medicine.

Dr. Mielke is currently an Associate Professor in the Department of Health Sciences Research, Division of Epidemiology, and the Department of Neurology at the Mayo Clinic in Rochester, MN. Dr. Mielke works as a translational epidemiologist to further understanding of the etiology and epidemiology of neurodegenerative diseases and neuropsychiatric disorders. A primary focus of her research is the identification and clinical translation of fluid and neuroimaging biomarkers for the diagnosis, prediction, and/or progression of neurodegenerative diseases. Much of her work has emphasized the utility of blood-based lipids, especially the role of sphingolipids (ceramides and sphingomyelins) in the development of AD, Parkinson’s disease, and Lewy Body Dementia. Dr. Mielke is the PI of several NIH- and Foundation-funded clinical- and epidemiological-based grants examining blood-based biomarkers of Alzheimer’s disease and other neurodegenerative conditions. Dr. Mielke also works to understand the sex differences in the epidemiology of neurodegenerative conditions and is a co-investigator of the Mayo Clinic Specialized Center of Research on Sex Differences.

 

Peter-Rabins

Peter V. Rabins, MD, MPH

Dr. Rabins’ career has focused on the study of psychiatric disorders in older persons. His research
focuses on the effectiveness of current therapies for Alzheimer disease, development of measures of
quality of life in persons with Alzheimer disease, and care of patients with late-stage dementia. He has
been a Johns Hopkins School of Medicine faculty member since 1978. He is Professor in the Department
of Psychiatry and director of the Division of Geriatric Psychiatry and Neuropsychiatry. He is the author
of more than 275 articles and book chapters. He is co-author of The 36 Hour Day (now in its 5th edition),
Practical Dementia Care and Getting Old Without Getting Anxious.





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Alan J. Russell, PhD

Dr. Russell has contributed to the interface between chemistry, biology, and material science. He is
the Highmark Distinguished Career Professor at Carnegie Mellon University. Earlier, he was founding
director of the University of Pittsburgh’s McGowan Institute for Regenerative Medicine. He is executive
director of the Pittsburgh Tissue Engineering Initiative, founder of three biotechnology companies and
has been a scientific adviser to FDA and the Department of Defense. He is editor-in-chief of Disruptive
Science and Technology. He was founding president of the Tissue Engineering and Regenerative
Medicine International Society and a past chair of the American Institute for Medical and Biological
Engineering College of Fellows.

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